Abeta-IN-1 is a novel, potent and orally active gamma-secretase modulator (GSM). Abeta-IN-1 potently reduced Abeta42 levels with an IC 50 value of 0.091 µM in cultured cells without inhibiting CYP3A4. Abeta-IN-1 shows a sustained pharmacokinetic profile.
Molekulargewicht:
483.77
Reinheit:
99.57%
CAS Nummer:
[2766509-32-2]
Formel:
C35H49N
Target-Kategorie:
Beta Amyloid|||Gamma-secretase
T63208
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