Abeta-IN-1 is a novel, potent and orally active gamma-secretase modulator (GSM). Abeta-IN-1 potently reduced Abeta42 levels with an IC 50 value of 0.091 µM in cultured cells without inhibiting CYP3A4. Abeta-IN-1 shows a sustained pharmacokinetic profile.
Molecular Weight:
483.77
Purity:
99.57%
CAS Number:
[2766509-32-2]
Formula:
C35H49N
Target:
Beta Amyloid|||Gamma-secretase
T63208
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