Selvigaltin, CAS [[1978336-95-6]]

Produktübersicht

• Artikelname: Selvigaltin, CAS [[1978336-95-6]]
• Artikelnummer: TGM-T63751
• Hersteller Artikelnummer: T63751
• Alternativnummer: TGM-T63751-1MLX10MM(INDMSO),TGM-T63751-1MG,TGM-T63751-5MG,TGM-T63751-10MG,TGM-T63751-25MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: GB1211

Produktbeschreibung

Selvigaltin (GB1211) is an orally administered, highly selective small-molecule inhibitor of galectin-3 (Gal-3) with an IC50 value of 12 nM in rabbits, exhibiting anticancer and anti-fibrotic activity. Selvigaltin reduces galectin-3 levels in the liver and decreases biomarkers of inflammation (cellular foci) and fibrosis (PSR, SHG), while simultaneously lowering the mRNA and protein expression of inflammatory and fibrotic biomarkers (IL-6, TGF-beta3, SNAI2, collagen). Selvigaltin also restores T-cell activity and reduces tumor growth and metastasis. Selvigaltin is suitable for use in studies of liver fibrosis, non-alcoholic steatohepatitis (NASH), and tumors.

Produkteigenschaften

• Molekulargewicht: 533.32
• Reinheit: 99.49%
• CAS Nummer: [1978336-95-6]
• Formel: C19H16BrF3N4O4S
• Target-Kategorie: Galectin|||Neuropeptide Y Receptor

Bilder

T63751