Selvigaltin, CAS [[1978336-95-6]]

Product Overview

• Article Name: Selvigaltin, CAS [[1978336-95-6]]
• Biozol Catalog Number: TGM-T63751
• Supplier Catalog Number: T63751
• Alternative Catalog Number: TGM-T63751-1MLX10MM(INDMSO),TGM-T63751-1MG,TGM-T63751-5MG,TGM-T63751-10MG,TGM-T63751-25MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: GB1211

Product Description

Selvigaltin (GB1211) is an orally administered, highly selective small-molecule inhibitor of galectin-3 (Gal-3) with an IC50 value of 12 nM in rabbits, exhibiting anticancer and anti-fibrotic activity. Selvigaltin reduces galectin-3 levels in the liver and decreases biomarkers of inflammation (cellular foci) and fibrosis (PSR, SHG), while simultaneously lowering the mRNA and protein expression of inflammatory and fibrotic biomarkers (IL-6, TGF-beta3, SNAI2, collagen). Selvigaltin also restores T-cell activity and reduces tumor growth and metastasis. Selvigaltin is suitable for use in studies of liver fibrosis, non-alcoholic steatohepatitis (NASH), and tumors.

Product Properties

• Molecular Weight: 533.32
• Purity: 99.49%
• CAS Number: [1978336-95-6]
• Formula: C19H16BrF3N4O4S
• Target: Galectin|||Neuropeptide Y Receptor

Images

T63751