FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 µM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16 inhibits the cystine/glutamate inverse transporter protein (system Xc-)-mediated exchange of intracellular glutamate for extracellular cystine.FA16 significantly inhibited tumor growth in a HepG2 xenograft tumor model. HepG2 xenograft tumor model significantly inhibited tumor growth.
Molekulargewicht:
468.54
Reinheit:
99.81%
Formel:
C22H27F3N4O2S
Target-Kategorie:
Ferroptosis
T64357
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
