FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 µM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16 inhibits the cystine/glutamate inverse transporter protein (system Xc-)-mediated exchange of intracellular glutamate for extracellular cystine.FA16 significantly inhibited tumor growth in a HepG2 xenograft tumor model. HepG2 xenograft tumor model significantly inhibited tumor growth.
Molecular Weight:
468.54
Purity:
99.81%
Formula:
C22H27F3N4O2S
Target:
Ferroptosis
T64357
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