JB061 is a nonmuscle myosin inhibitor, demonstrating selective inhibitory activity with IC50 values of 4.4 µM (Cardiac muscle myosin), 9.1 µM (Skeletal muscle myosin), and >100 µM (Smooth muscle myosin II). It exhibits limited efficacy in reducing ATPase activity, with an IC50 exceeding 200 µM. Furthermore, JB061 displays cytotoxic effects on COS-7 cells, evidenced by an IC50 value of 39 µM.
Molekulargewicht:
323.34
Reinheit:
99.67%
Formel:
C19H17NO4
Target-Kategorie:
Myosin
T67951
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
