JB061 is a nonmuscle myosin inhibitor, demonstrating selective inhibitory activity with IC50 values of 4.4 µM (Cardiac muscle myosin), 9.1 µM (Skeletal muscle myosin), and >100 µM (Smooth muscle myosin II). It exhibits limited efficacy in reducing ATPase activity, with an IC50 exceeding 200 µM. Furthermore, JB061 displays cytotoxic effects on COS-7 cells, evidenced by an IC50 value of 39 µM.
Molecular Weight:
323.34
Purity:
99.67%
Formula:
C19H17NO4
Target:
Myosin
T67951
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