KW-2450 free base, CAS [[904899-25-8]]

Artikelnummer: TGM-T68405
Artikelname: KW-2450 free base, CAS [[904899-25-8]]
Artikelnummer: TGM-T68405
Hersteller Artikelnummer: T68405
Alternativnummer: TGM-T68405-1MG,TGM-T68405-2MG,TGM-T68405-5MG,TGM-T68405-10MG,TGM-T68405-25MG,TGM-T68405-50MG
Hersteller: TargetMol
Kategorie: Biochemikalien
KW-2450 free base is an orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity. IGF-1R/IR inhibitor KW-2450 free base selectively binds to and inhibits the activities of IGF-1R and IR, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. IGF-R1 and IR tyrosine kinases, overexpressed in a variety of human cancers, play significant roles in the stimulation of cellular proliferation, oncogenic transformation, and suppression of apoptosis.
Molekulargewicht: 515.63
Reinheit: 98.93%
CAS Nummer: [904899-25-8]
Formel: C28H29N5O3S
Target-Kategorie: Apoptosis|||Aurora Kinase|||IGF-1R
T68405