KW-2450 free base, CAS [[904899-25-8]]

Product Overview

• Article Name: KW-2450 free base, CAS [[904899-25-8]]
• Biozol Catalog Number: TGM-T68405
• Supplier Catalog Number: T68405
• Alternative Catalog Number: TGM-T68405-1MG,TGM-T68405-2MG,TGM-T68405-5MG,TGM-T68405-10MG,TGM-T68405-25MG,TGM-T68405-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

KW-2450 free base is an orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity. IGF-1R/IR inhibitor KW-2450 free base selectively binds to and inhibits the activities of IGF-1R and IR, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. IGF-R1 and IR tyrosine kinases, overexpressed in a variety of human cancers, play significant roles in the stimulation of cellular proliferation, oncogenic transformation, and suppression of apoptosis.

Product Properties

• Molecular Weight: 515.63
• Purity: 98.93%
• CAS Number: [904899-25-8]
• Formula: C28H29N5O3S
• Target: Apoptosis|||Aurora Kinase|||IGF-1R

Images

T68405