Mafosfamide sodium is a synthetic oxazaphosphorine derivative with antineoplastic properties. Mafosfamide sodium alkylates DNA, forming DNA cross-links and inhibiting DNA synthesis. Although closely related to cyclophosphamide, Mafosfamide sodium, unlike cyclophosphamide, does not require hepatic activation to generate its active metabolite 4-hydroxy-cyclophosphamide, accordingly, Mafosfamide sodium is potentially useful in the intrathecal treatment of neoplastic meningitis.
Molekulargewicht:
423.24
CAS Nummer:
[84211-05-2]
Formel:
C9H18Cl2N2NaO5PS2
Target-Kategorie:
Others
T68592
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