Mafosfamide sodium is a synthetic oxazaphosphorine derivative with antineoplastic properties. Mafosfamide sodium alkylates DNA, forming DNA cross-links and inhibiting DNA synthesis. Although closely related to cyclophosphamide, Mafosfamide sodium, unlike cyclophosphamide, does not require hepatic activation to generate its active metabolite 4-hydroxy-cyclophosphamide, accordingly, Mafosfamide sodium is potentially useful in the intrathecal treatment of neoplastic meningitis.
Molecular Weight:
423.24
CAS Number:
[84211-05-2]
Formula:
C9H18Cl2N2NaO5PS2
Target:
Others
T68592
* VAT and and shipping costs not included. Errors and price changes excepted
