UNC10112785, CAS [[748142-06-5]]

Produktübersicht

• Artikelname: UNC10112785, CAS [[748142-06-5]]
• Artikelnummer: TGM-T68758
• Hersteller Artikelnummer: T68758
• Alternativnummer: TGM-T68758-1MG,TGM-T68758-5MG,TGM-T68758-10MG,TGM-T68758-25MG,TGM-T68758-50MG,TGM-T68758-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: UNC-10112785 , UNC 10112785

Produktbeschreibung

UNC10112785 is a novel and potent inhibitor of CDK8, CDK19, and CDK9 with IC50 values of 1.05 nM, 2.67 nM, and 19.9 nM, respectively, inducing MYC protein loss via both transcriptional and post-translational mechanisms. UNC10112785 suppresses pancreatic ductal adenocarcinoma (PDAC) growth under both anchorage-dependent and anchorage-independent conditions, causing substantial MYC depletion in two-dimensional and three-dimensional cell culture models.

Produkteigenschaften

• Molekulargewicht: 330.39
• Reinheit: 98.12%
• CAS Nummer: [748142-06-5]
• Formel: C19H18N6
• Target-Kategorie: CDK

Bilder

T68758

T68758