UNC10112785, CAS [[748142-06-5]]

Product Overview

• Article Name: UNC10112785, CAS [[748142-06-5]]
• Biozol Catalog Number: TGM-T68758
• Supplier Catalog Number: T68758
• Alternative Catalog Number: TGM-T68758-1MG,TGM-T68758-5MG,TGM-T68758-10MG,TGM-T68758-25MG,TGM-T68758-50MG,TGM-T68758-100MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: UNC-10112785 , UNC 10112785

Product Description

UNC10112785 is a novel and potent inhibitor of CDK8, CDK19, and CDK9 with IC50 values of 1.05 nM, 2.67 nM, and 19.9 nM, respectively, inducing MYC protein loss via both transcriptional and post-translational mechanisms. UNC10112785 suppresses pancreatic ductal adenocarcinoma (PDAC) growth under both anchorage-dependent and anchorage-independent conditions, causing substantial MYC depletion in two-dimensional and three-dimensional cell culture models.

Product Properties

• Molecular Weight: 330.39
• Purity: 98.12%
• CAS Number: [748142-06-5]
• Formula: C19H18N6
• Target: CDK

Images

T68758

T68758