DMGF, also known as 7,7-dimethoxyagastisfavone, is a biflavonoid isolated from Taxus * media cv. Hicksii. DMGF induces apoptotic and autophagic cell death. DMGF could effectively attenuate the motility of B16F10 cells, and the results of real-time PCR revealed that DMGF also suppressed the expressions of matrix metalloproteinase-2 (MMP-2). MGF can inhibit the metastasis of highly invasive melanoma cancer cells through the down-regulation of F-actin polymerization DMGF may be further developed to serve as a chemoprevention drug for patients with metastatic melanoma.
Molekulargewicht:
566.51
CAS Nummer:
[41679-06-5]
Formel:
C32H22O10
Target-Kategorie:
Others
T69269
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
