DMGF, also known as 7,7-dimethoxyagastisfavone, is a biflavonoid isolated from Taxus * media cv. Hicksii. DMGF induces apoptotic and autophagic cell death. DMGF could effectively attenuate the motility of B16F10 cells, and the results of real-time PCR revealed that DMGF also suppressed the expressions of matrix metalloproteinase-2 (MMP-2). MGF can inhibit the metastasis of highly invasive melanoma cancer cells through the down-regulation of F-actin polymerization DMGF may be further developed to serve as a chemoprevention drug for patients with metastatic melanoma.
Molecular Weight:
566.51
CAS Number:
[41679-06-5]
Formula:
C32H22O10
Target:
Others
T69269
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