GDC-2394 sodium salt is an orally active selective NLRP3 inhibitor that concurrently inhibits IL-1beta with IC50 values of 0.4 µM (human) and 0.1 µM (mouse). This compound specifically inhibits NLRP3-induced caspase-1 activity without affecting NLRC4-dependent inflammasome activation.
Molekulargewicht:
453.49
Reinheit:
99.50%
CAS Nummer:
[2238822-08-5]
Formel:
C20H24N5NaO4S
Target-Kategorie:
IL Receptor|||NOD
T69745L
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten