Flavokawain B, CAS [[1775-97-9]]

Artikelnummer: TGM-T6S0735
Artikelname: Flavokawain B, CAS [[1775-97-9]]
Artikelnummer: TGM-T6S0735
Hersteller Artikelnummer: T6S0735
Alternativnummer: TGM-T6S0735-1MG,TGM-T6S0735-5MG,TGM-T6S0735-10MG,TGM-T6S0735-25MG,TGM-T6S0735-50MG,TGM-T6S0735-100MG,TGM-T6S0735-500MG
Hersteller: TargetMol
Kategorie: Biochemikalien
Alternative Synonym: Flavokawin B , Flavokavain B , 2-Hydroxy-4,6-Dimethoxychalcone
1. Flavokawain B (Flavokavain B) has potent anti-inflammatory activity, can significantly inhibit production of NO and PGE2 in LPS-induced RAW 264.7 cells. 2. Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-kappaB and MAPK signaling pathways. 3. Flavokawain B induces apoptosis, has the potential usefulness of FKB for prevention and treatment of hormone-refractory prostate cancer in an adjuvant setting. 4. Flavokawain B acts through ROS generation and GADD153 up-regulation to regulate the expression of Bcl-2 family members, thereby inducing mitochondrial dysfunction and apoptosis in HCT116 cells.
Molekulargewicht: 284.31
Reinheit: >99.99%
CAS Nummer: [1775-97-9]
Formel: C17H16O4
Target-Kategorie: NF-kappaB|||PI3K|||ROS|||MMP|||Caspase|||Akt|||Apoptosis|||p38 MAPK|||PARP|||Bcl-2 Family
T6S0735