AT-1001, CAS [[1314801-63-2]]

Produktübersicht

• Artikelname: AT-1001, CAS [[1314801-63-2]]
• Artikelnummer: TGM-T70987
• Hersteller Artikelnummer: T70987
• Alternativnummer: TGM-T70987-25MG,TGM-T70987-50MG,TGM-T70987-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

AT-1001 is an alpha3beta4 nAChR partial agonist. AT-1001 attenuates stress-induced reinstatement of nicotine seeking in a rat model of relapse and induces minimal withdrawal in dependent rats. AT-1001 also potently and reversibly blocks epibatidine-induced inward currents in HEK cells transfected with alpha3beta4 nAChR. Importantly, AT-1001 potently and dose-dependently blocks nicotine self-administration in rats, without affecting food responding. When tested in a nucleus accumbens (NAcs) synaptosomal preparation, AT-1001 inhibits nicotine-induced [H]dopamine release poorly and at significantly higher concentrations compared with mecamylamine and conotoxin MII.

Produkteigenschaften

• Molekulargewicht: 309.24
• Reinheit: 98.26%
• CAS Nummer: [1314801-63-2]
• Formel: C15H21BrN2
• Target-Kategorie: AChR|||Others

Bilder

T70987