SGK1 inhibitor, CAS [[1426214-51-8]]

Produktübersicht

• Artikelname: SGK1 inhibitor, CAS [[1426214-51-8]]
• Artikelnummer: TGM-T71947
• Hersteller Artikelnummer: T71947
• Alternativnummer: TGM-T71947-1MG,TGM-T71947-5MG,TGM-T71947-10MG,TGM-T71947-25MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

SGK1 inhibitor is an inhibitor of serum- and glucocorticoid-regulated kinase 1 (SGK1) and SGK2. It is selective for SGK1 and SGK2 over SGK3 in the presence of a high concentration of ATP. SGK1 inhibitor prevents phosphorylation of GSK3beta in U2OS cells and decreases cell viability in BYL719-insensitive HCC1954 cells when used in combination with the PI3Kalpha inhibitor BYL719. SGK1 inhibitor reduces tumor growth in an HCC1954 mouse xenograft model when administered in combination with BYL719.

Produkteigenschaften

• Molekulargewicht: 435.29
• CAS Nummer: [1426214-51-8]
• Formel: C17H12Cl2N6O2S
• Target-Kategorie: Others|||SGK

Bilder

T71947