SGK1 inhibitor, CAS [[1426214-51-8]]

Product Overview

• Article Name: SGK1 inhibitor, CAS [[1426214-51-8]]
• Biozol Catalog Number: TGM-T71947
• Supplier Catalog Number: T71947
• Alternative Catalog Number: TGM-T71947-1MG,TGM-T71947-5MG,TGM-T71947-10MG,TGM-T71947-25MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

SGK1 inhibitor is an inhibitor of serum- and glucocorticoid-regulated kinase 1 (SGK1) and SGK2. It is selective for SGK1 and SGK2 over SGK3 in the presence of a high concentration of ATP. SGK1 inhibitor prevents phosphorylation of GSK3beta in U2OS cells and decreases cell viability in BYL719-insensitive HCC1954 cells when used in combination with the PI3Kalpha inhibitor BYL719. SGK1 inhibitor reduces tumor growth in an HCC1954 mouse xenograft model when administered in combination with BYL719.

Product Properties

• Molecular Weight: 435.29
• CAS Number: [1426214-51-8]
• Formula: C17H12Cl2N6O2S
• Target: Others|||SGK

Images

T71947