(+)-Norfenfluramine, the principal hepatic metabolite of (+)-fenfluramine, acts as a selective agonist for the 5-HT2B receptor, exhibiting a potent K i of 11.2 nM. It significantly promotes the hydrolysis of inositol phosphates and heightens intracellular Ca2+ levels. This compound is valuable in the study of primary pulmonary hypertension and valvular heart disease.
Molekulargewicht:
203.2
CAS Nummer:
[19036-73-8]
Formel:
C10H12F3N
Target-Kategorie:
5-HT Receptor
T72510
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten