(R)-Afatinib, CAS [[439081-17-1]]

Produktübersicht

• Artikelname: (R)-Afatinib, CAS [[439081-17-1]]
• Artikelnummer: TGM-T72912
• Hersteller Artikelnummer: T72912
• Alternativnummer: TGM-T72912-25MG,TGM-T72912-50MG,TGM-T72912-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: (R)-BIBW 2992

Produktbeschreibung

(R)-Afatinib ((R)-BIBW 2992), an isomer of Afatinib, is a potent, orally administered, irreversible inhibitor targeting the ErbB family (EGFR and HER2) with IC50 values of 0.5 nM for EGFR wt, 0.4 nM for EGFR L858R, 10 nM for EGFR L858R/T790M, and 14 nM for HER2, holding potential for research into esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC), and gastric cancer [1].

Produkteigenschaften

• Molekulargewicht: 485.94
• CAS Nummer: [439081-17-1]
• Formel: C24H25ClFN5O3
• Target-Kategorie: p38 MAPK|||EGFR|||Others|||c-Met/HGFR

Bilder

T72912