SS47, a PROTAC-based HPK1 degrader, induces proteasome-mediated HPK1 degradation and significantly enhances the in vivo antitumor efficacy of BCMA CAR-T cell research. HPK1, an immunosuppressive regulatory kinase, is a promising target for cancer immunotherapies [1].
Molekulargewicht:
953.07
CAS Nummer:
[2636072-62-1]
Formel:
C49H56N6O12S
Target-Kategorie:
Others|||PROTACs|||MAPK
T74508
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
