SS47, a PROTAC-based HPK1 degrader, induces proteasome-mediated HPK1 degradation and significantly enhances the in vivo antitumor efficacy of BCMA CAR-T cell research. HPK1, an immunosuppressive regulatory kinase, is a promising target for cancer immunotherapies [1].
Molecular Weight:
953.07
CAS Number:
[2636072-62-1]
Formula:
C49H56N6O12S
Target:
Others|||PROTACs|||MAPK
T74508
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