alpha1A-AR Degrader 9c is a potent, selective, and reversible PROTAC degrader targeting the alpha1A adrenergic receptor (alpha1A-AR) with a DC50 of 2.86 µM. It promotes the proteasomal degradation of the alpha1A-AR and exhibits anti-proliferative effects against PC-3 cells, presenting an IC50 value of 6.12 µM. This compound demonstrates antitumor activity and holds potential for prostate cancer research [1].
Molekulargewicht:
829.82
CAS Nummer:
[2863635-02-1]
Formel:
C38H43N11O11
Target-Kategorie:
Adrenergic Receptor|||PROTACs
T74557
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
