alpha1A-AR Degrader 9c is a potent, selective, and reversible PROTAC degrader targeting the alpha1A adrenergic receptor (alpha1A-AR) with a DC50 of 2.86 µM. It promotes the proteasomal degradation of the alpha1A-AR and exhibits anti-proliferative effects against PC-3 cells, presenting an IC50 value of 6.12 µM. This compound demonstrates antitumor activity and holds potential for prostate cancer research [1].
Molecular Weight:
829.82
CAS Number:
[2863635-02-1]
Formula:
C38H43N11O11
Target:
Adrenergic Receptor|||PROTACs
T74557
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