A947 is a potent and selective SMARCA2 protein hydrolysis-targeted chimeric molecule (PROTAC) that induces the degradation of SMARCA2 by binding to VHL E3 ubiquitin ligase, with significant antitumor activity in vivo and in vitro, especially in SMARCA4-mutant non-small cell lung cancer (NSCLC) cells.
Molekulargewicht:
1121.4
Reinheit:
98.84%
CAS Nummer:
[2378056-80-3]
Formel:
C61H76N12O7S
Target-Kategorie:
PROTACs|||Epigenetic Reader Domain|||Apoptosis
T74686
T74686
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
