YS-49 (monohydrate) is an isoquinoline compound alkaloid that functions as a PI3K/Akt activator, specifically targeting a downstream effect of RhoA, to mitigate the activation of RhoA/PTEN in 3-methylcholanthrene-treated cells. It also prevents the angiotensin II (Ang II)-induced proliferation of vascular smooth muscle cells (VSMCs) by promoting the expression of heme oxygenase (HO)-1. Additionally, YS-49 exerts a significant positive inotropic effect by stimulating cardiac beta-adrenoceptors, showcasing its multifaceted pharmacological activities [1] [2] [3].
Molekulargewicht:
404.3
Formel:
C20H22BrNO3
Target-Kategorie:
Akt|||RAAS|||Others|||PI3K|||Adrenergic Receptor
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
