Timigutuzumab, CAS [[1665274-14-5]] Preis auf Anfrage

Produktübersicht

• Artikelname: Timigutuzumab, CAS [[1665274-14-5]] Preis auf Anfrage
• Artikelnummer: TGM-T76977
• Hersteller Artikelnummer: T76977
• Alternativnummer: TGM-T76977-5MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: TrastuzuMab-GEX , GEXMab73 , GT-MAb7.3-GEX

Produktbeschreibung

Timigutuzumab (GEXMab73) is a glyco-optimized monoclonal antibody targeting the human epidermal growth factor receptor 2 (ErbB2/HER2). Through glyco-engineering (typically afucosylation), the antibodys Fc region exhibits enhanced binding affinity for the FcgammaRIIIa receptors on immune effector cells, such as natural killer (NK) cells. This optimization significantly boosts Antibody-Dependent Cell-mediated Cytotoxicity (ADCC), enabling potent tumor cell lysis even in cases with low HER2 expression levels. Timigutuzumab is designed to overcome resistance to conventional anti-HER2 therapies and provide an improved therapeutic option for solid tumors.

Produkteigenschaften

• CAS Nummer: [1665274-14-5]
• Target-Kategorie: Others