PB118 has the capacity to effectively clear Abeta deposits by augmenting phagocytosis, enhance the tubulin/microtubule network through increased acetyl alpha-tubulin levels, modulate various inflammation-associated cytokines and chemokines, and notably diminish phospho-tau (p-tau) levels linked to Alzheimers disease (AD). The IC50 of PB118 for HDAC6 is 5.6 nM.
Molekulargewicht:
314.35
Formel:
C18H19FN2O2
Target-Kategorie:
Others|||HDAC
T78552
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
