ERD-3111 (Compound 44), an orally active PROTAC ERalpha degrader (DC50: 0.5 nM), exhibits efficacy in inhibiting tumor growth in both the parental MCF-7 xenograft model harboring wild-type ER and two ESR1-mutated mouse models. This compound has utility in the investigation of ER+ breast cancer [1].
Molekulargewicht:
854.89
CAS Nummer:
[2832865-25-3]
Formel:
C45H46F4N8O5
Target-Kategorie:
PROTACs|||Estrogen Receptor/ERR
T78824
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
