SLMP53-2 is a mutant p53 reactivator that restores the wild-type-like conformation and DNA-binding ability of mutp53-Y220C through enhanced interaction with Hsp70, thereby reinstating p53s transcriptional activity. This compound induces cell cycle arrest, apoptosis, and endoplasmic reticulum (ER) stress, displaying antitumor activity [1] [2].
Molekulargewicht:
394.47
CAS Nummer:
[1826116-38-4]
Formel:
C26H22N2O2
Target-Kategorie:
Others|||MDM-2/p53|||Apoptosis
T79013
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten