SLMP53-2 is a mutant p53 reactivator that restores the wild-type-like conformation and DNA-binding ability of mutp53-Y220C through enhanced interaction with Hsp70, thereby reinstating p53s transcriptional activity. This compound induces cell cycle arrest, apoptosis, and endoplasmic reticulum (ER) stress, displaying antitumor activity [1] [2].
Molecular Weight:
394.47
CAS Number:
[1826116-38-4]
Formula:
C26H22N2O2
Target:
Others|||MDM-2/p53|||Apoptosis
T79013
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