NF-kappaB-IN-11, CAS [[2768833-35-6]]

Produktübersicht

• Artikelname: NF-kappaB-IN-11, CAS [[2768833-35-6]]
• Artikelnummer: TGM-T79671
• Hersteller Artikelnummer: T79671
• Alternativnummer: TGM-T79671-25MG,TGM-T79671-50MG,TGM-T79671-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

NF-kappaB-IN-11 (Compound 3i) is an inhibitor of NF-kappaB, effectively blocking TNF-alpha-induced NF-kappaB pathway activation and nuclear translocation of NF-kappaB, alongside reducing expression levels of phospho-IKK, IkappaBalpha, and NF-kappaB p65. Demonstrating anti-inflammatory properties, it mitigates dextran sulfate sodium-induced colitis in mice and exhibits a maximum tolerated dose (MTD) exceeding 1852 mg/kg in acute toxicity assays when administered orally (p.o.) [1].

Produkteigenschaften

• Molekulargewicht: 326.34
• CAS Nummer: [2768833-35-6]
• Formel: C19H18O5
• Target-Kategorie: NF-kappaB

Bilder

T79671