LB244 is a homologue of BB-Cl-amidine and functions as an orally effective STING inhibitor with an EC50 value of 0.8 µM, capable of suppressing STING-dependent inflammatory signaling, although pharmacokinetic studies indicate limited oral activity in mice, making it a useful tool for mechanistic investigations of innate immunity and inflammatory disease models.
Molekulargewicht:
537.57
CAS Nummer:
[3074622-05-9]
Formel:
C30H27N5O5
Target-Kategorie:
STING
T79730
T79730
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
