LB244 is a homologue of BB-Cl-amidine and functions as an orally effective STING inhibitor with an EC50 value of 0.8 µM, capable of suppressing STING-dependent inflammatory signaling, although pharmacokinetic studies indicate limited oral activity in mice, making it a useful tool for mechanistic investigations of innate immunity and inflammatory disease models.
Molecular Weight:
537.57
CAS Number:
[3074622-05-9]
Formula:
C30H27N5O5
Target:
STING
T79730
T79730
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