Polzastobart, CAS [[2640981-19-5]]

Artikelnummer: TGM-T81423
Artikelname: Polzastobart, CAS [[2640981-19-5]]
Artikelnummer: TGM-T81423
Hersteller Artikelnummer: T81423
Alternativnummer: TGM-T81423-1MG, TGM-T81423-5MG, TGM-T81423-10MG, TGM-T81423-25MG, TGM-T81423-50MG
Hersteller: TargetMol
Kategorie: Biochemikalien
Alternative Synonym: JTX8064 , JTX 8064
Polzastobart (JTX-8064) is a humanized monoclonal antibody targeting LILRB2 that blocks its interaction with ligands and MHC class I molecules. Polzastobart blocks LILRB2-mediated immunosuppressive signaling, promotes the polarization of macrophages toward a pro-inflammatory phenotype, and enhances their production of pro-inflammatory cytokines. Polzastobart is a macrophage immune checkpoint inhibitor. Polzastobart exhibits antitumor activity and is being investigated for the treatment of refractory solid tumors.
Reinheit: 97.81%
CAS Nummer: [2640981-19-5]
Target-Kategorie: Others
T81423