Polzastobart, CAS [[2640981-19-5]]

Product Overview

• Article Name: Polzastobart, CAS [[2640981-19-5]]
• Biozol Catalog Number: TGM-T81423
• Supplier Catalog Number: T81423
• Alternative Catalog Number: TGM-T81423-1MG, TGM-T81423-5MG, TGM-T81423-10MG, TGM-T81423-25MG, TGM-T81423-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: JTX8064 , JTX 8064

Product Description

Polzastobart (JTX-8064) is a humanized monoclonal antibody targeting LILRB2 that blocks its interaction with ligands and MHC class I molecules. Polzastobart blocks LILRB2-mediated immunosuppressive signaling, promotes the polarization of macrophages toward a pro-inflammatory phenotype, and enhances their production of pro-inflammatory cytokines. Polzastobart is a macrophage immune checkpoint inhibitor. Polzastobart exhibits antitumor activity and is being investigated for the treatment of refractory solid tumors.

Product Properties

• Purity: 97.81%
• CAS Number: [2640981-19-5]
• Target: Others

Images

T81423