Tianeptine Metabolite MC5 sodium, CAS [[115220-11-6]]

Produktübersicht

• Artikelname: Tianeptine Metabolite MC5 sodium, CAS [[115220-11-6]]
• Artikelnummer: TGM-T83676
• Hersteller Artikelnummer: T83676
• Alternativnummer: TGM-T83676-1MG,TGM-T83676-5MG,TGM-T83676-10MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

Tianeptine metabolite MC5, an active derivative of the atypical antidepressant tianeptine produced through beta-oxidation, exhibits selective G protein activation in bioluminescence resonance energy transfer (BRET) assays. Utilizing HEK293T cells expressing the human µ-opioid receptor (MOR) over the human delta-opioid receptor (DOR, EC50s = 0.454 and >100 µM, respectively), it demonstrates specificity. Moreover, this metabolite reduces immobility in wild-type mice during the forced swim test at a dose of 30 mg/kg, an effect not observed in MOR knockout mice, suggesting its antidepressant-like activity is MOR-dependent.

Produkteigenschaften

• Molekulargewicht: 430.88
• CAS Nummer: [115220-11-6]
• Formel: C19H20ClN2O4S.Na
• Target-Kategorie: Drug Metabolite

Bilder

T83676