Tianeptine Metabolite MC5 sodium, CAS [[115220-11-6]]
Biozol Catalog Number:
TGM-T83676
Supplier Catalog Number:
T83676
Alternative Catalog Number:
TGM-T83676-1MG,TGM-T83676-5MG,TGM-T83676-10MG
Manufacturer:
TargetMol
Category:
Biochemikalien
Tianeptine metabolite MC5, an active derivative of the atypical antidepressant tianeptine produced through beta-oxidation, exhibits selective G protein activation in bioluminescence resonance energy transfer (BRET) assays. Utilizing HEK293T cells expressing the human µ-opioid receptor (MOR) over the human delta-opioid receptor (DOR, EC50s = 0.454 and >100 µM, respectively), it demonstrates specificity. Moreover, this metabolite reduces immobility in wild-type mice during the forced swim test at a dose of 30 mg/kg, an effect not observed in MOR knockout mice, suggesting its antidepressant-like activity is MOR-dependent.
Molecular Weight:
430.88
CAS Number:
[115220-11-6]
Formula:
C19H20ClN2O4S.Na
Target:
Drug Metabolite
T83676
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