8-bromo NAD+ sodium, CAS [[2022926-16-3]]

Produktübersicht

• Artikelname: 8-bromo NAD+ sodium, CAS [[2022926-16-3]]
• Artikelnummer: TGM-T83798
• Hersteller Artikelnummer: T83798
• Alternativnummer: TGM-T83798-7400UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: 8-bromo Nicotinamide adenine dinucleotide , N(8-bromo-A)D+

Produktbeschreibung

8-Bromo NAD+ serves as a prodrug for the cyclic ADP-ribose (cADPR) inhibitor, 8-bromo cADPR, undergoing conversion to its active form by the enzyme CD38. At a concentration of 1 mM, it effectively inhibits the rise in intracellular calcium levels and chemotaxis triggered by N-formyl-Met-Leu-Phe (fMLP) in mouse bone marrow-derived neutrophils. Furthermore, when applied at 100 µM, this compound reduces LPS-induced nitrite production and decreases the secretion of TNF-alpha and IL-2 in mouse primary microglial cells.

Produkteigenschaften

• Molekulargewicht: 764.3
• CAS Nummer: [2022926-16-3]
• Formel: C21H25BrN7O14P2.Na
• Target-Kategorie: Others|||Calcium Channel

Bilder

T83798