JQ1-FITC, a fluorescent BET bromodomain probe, exhibits high affinity binding to BRD4(BD1) and BRD4(BD2), with KD,app values of 6.5 nM and 5.8 nM respectively, as determined using GST-tagged BRD4 proteins in a CoraFluorTR-FRET assay, for BRD4(BD1), the value is 58.7 nM in a fluorescence anisotropy assay. It has excitation and emission maxima (lambda) of 495 nm and 525 nm.
Molekulargewicht:
1106.58
Formel:
C50H50ClN7O9S2.CF3CO2H
Target-Kategorie:
Others
T83931
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
