Prostaglandin F2alpha ethyl amide, CAS [[54130-36-8]] Preis auf Anfrage
Artikelnummer:
TGM-T84652
Hersteller Artikelnummer:
T84652
Alternativnummer:
TGM-T84652-10MG,TGM-T84652-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
Alternative Synonym:
Dinoprost ethyl amide
Prostaglandin F2alphaethyl amide (PGF2alpha-NEt), a PGF2alpha analog featuring an N-ethyl amide modification at the C-1 carboxyl group, possesses ocular hypotensive activity similar to PG esters. Introduced as alternative prostaglandin ocular hypotensive prodrugs, PGF2alpha-NEt and other PG N-ethyl amides, contrary to claims of not converting to free acids in vivo, have been demonstrated by our laboratory studies to undergo conversion by bovine and human corneal tissue into the respective free acids at a rate of approximately 2.5 µg/g corneal tissue/hr. This suggests PGF2alpha-NEt is expected to elicit typical PGF2alpha free acid intraocular effects, albeit with slower hydrolysis kinetics characteristic of PG N-amides.
Molekulargewicht:
381.6
CAS Nummer:
[54130-36-8]
Formel:
C22H39NO4
Target-Kategorie:
Others|||Prostaglandin Receptor
T84652
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