Prostaglandin F2alpha ethyl amide, CAS [[54130-36-8]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T84652
Supplier Catalog Number:
T84652
Alternative Catalog Number:
TGM-T84652-10MG,TGM-T84652-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
Alternative Names:
Dinoprost ethyl amide
Prostaglandin F2alphaethyl amide (PGF2alpha-NEt), a PGF2alpha analog featuring an N-ethyl amide modification at the C-1 carboxyl group, possesses ocular hypotensive activity similar to PG esters. Introduced as alternative prostaglandin ocular hypotensive prodrugs, PGF2alpha-NEt and other PG N-ethyl amides, contrary to claims of not converting to free acids in vivo, have been demonstrated by our laboratory studies to undergo conversion by bovine and human corneal tissue into the respective free acids at a rate of approximately 2.5 µg/g corneal tissue/hr. This suggests PGF2alpha-NEt is expected to elicit typical PGF2alpha free acid intraocular effects, albeit with slower hydrolysis kinetics characteristic of PG N-amides.
Molecular Weight:
381.6
CAS Number:
[54130-36-8]
Formula:
C22H39NO4
Target:
Others|||Prostaglandin Receptor
T84652
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