Senexin A hydrochloride functions as a selective inhibitor of CDK8/19, with an IC 50 of 280 nM for CDK8, and specifically inhibits p21-induced transcription without affecting other biological effects of p21. Additionally, it suppresses CMV-GFP induction and the stimulatory activity of the consensus NF-kappaB-dependent promoters [1] [2].
Molekulargewicht:
310.78
CAS Nummer:
[1780390-76-2]
Formel:
C17H15ClN4
Target-Kategorie:
CDK|||Others
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
