()-N-desmethyl Venlafaxine hydrochloride, CAS [[93413-90-2]] Preis auf Anfrage

Artikelnummer: TGM-T84941
Artikelname: ()-N-desmethyl Venlafaxine hydrochloride, CAS [[93413-90-2]] Preis auf Anfrage
Artikelnummer: TGM-T84941
Hersteller Artikelnummer: T84941
Alternativnummer: TGM-T84941-10MG,TGM-T84941-50MG
Hersteller: TargetMol
Kategorie: Biochemikalien
Alternative Synonym: Wy 45494
()-N-desmethyl Venlafaxine, a minor active metabolite of venlafaxine, serves as a selective norepinephrine and serotonin reuptake inhibitor (SNRI). Generated through the metabolization by the cytochrome P450 (CYP) isoform CYP3A4, it exhibits reuptake inhibition of norepinephrine and serotonin in rat synaptosome preparations, demonstrated by IC50 values of 4.7 and 1.6 µM, respectively. Clinically, it has been shown to counteract reserpine-induced hypothermia in mice, displaying efficacy at a minimum effective dose (MED) of 10 mg/kg.
Molekulargewicht: 299.836
CAS Nummer: [93413-90-2]
Formel: C16H26ClNO2
Target-Kategorie: Others
T84941