()-N-desmethyl Venlafaxine hydrochloride, CAS [[93413-90-2]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T84941
Supplier Catalog Number:
T84941
Alternative Catalog Number:
TGM-T84941-10MG,TGM-T84941-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
Alternative Names:
Wy 45494
()-N-desmethyl Venlafaxine, a minor active metabolite of venlafaxine, serves as a selective norepinephrine and serotonin reuptake inhibitor (SNRI). Generated through the metabolization by the cytochrome P450 (CYP) isoform CYP3A4, it exhibits reuptake inhibition of norepinephrine and serotonin in rat synaptosome preparations, demonstrated by IC50 values of 4.7 and 1.6 µM, respectively. Clinically, it has been shown to counteract reserpine-induced hypothermia in mice, displaying efficacy at a minimum effective dose (MED) of 10 mg/kg.
Molecular Weight:
299.836
CAS Number:
[93413-90-2]
Formula:
C16H26ClNO2
Target:
Others
T84941
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