FGFR-IN-13, CAS [[2962941-25-7]]

Produktübersicht

• Artikelname: FGFR-IN-13, CAS [[2962941-25-7]]
• Artikelnummer: TGM-T86425
• Hersteller Artikelnummer: T86425
• Alternativnummer: TGM-T86425-25MG, TGM-T86425-50MG, TGM-T86425-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

FGFR-IN-13 (compound III-30), an irreversible covalent inhibitor of the fibroblast growth factor receptor (FGFR), effectively modulates signaling through FGFR1 (IC 50 = 0.20 0.02 nM) and FGFR4 (IC 50 = 0.40 0.03 nM). It suppresses the expression of crucial proteins such as total-PARP and Bcl-2, while enhancing the expression of Cleaved-PARP and Bax in a dose-dependent manner. Notably, FGFR-IN-13 demonstrates considerable antitumor and oral activity [1].

Produkteigenschaften

• Molekulargewicht: 415.44
• CAS Nummer: [2962941-25-7]
• Formel: C23H21N5O3
• Target-Kategorie: FGFR