HDAC6-IN-37 (compound W5), an HDAC6 inhibitor, exhibits neuroprotective properties. It effectively restores the morphology of hippocampal neurons and diminishes the expression of Abeta, Tau, and p-Tau proteins in the hippocampus of AD rats. Additionally, it prevents the formation of senile plaques and neurofibrillary tangles. Consequently, HDAC6-IN-37 ameliorates the symptoms in the Abeta/Cu 2+ -induced AD rat model, regulates oxidative stress, and restores balance to neurotransmitter levels in brain tissue [1].
Molekulargewicht:
385.87
CAS Nummer:
[2986486-82-0]
Formel:
C19H16ClN3O2S
Target-Kategorie:
HDAC
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
